We have missed a cycle of grant review, but we should be able to recover this year. Research projects will be delayed but in most cases not irreparably harmed. For most scientists, coming to NIMH means sacrificing salary and working very long hours for the opportunity to have enormous impact. There was something about the furlough that left even the most self-sacrificing public servant feeling dispensable and devalued. No job, no impact. The long-term impact of the shutdown may be on morale.